• If we could afford to apply what we already know – with no more research – worldwide health would be improved and millions of lives saved. That would be good news indeed. It would be of more interest and welcomed by all members. Prevention, early diagnosis, and effective treatment are available – at a price - for common serious illnesses like heart disease, most cancers, and infections like malaria, TB, and HIV / AIDS.
• However, tissue and DNA samples linked to a personal medical database and test results should be able to uncover useful information. Drug companies and research workers may discover new drugs from looking at genetic variations in people with a particular disease. Disease patterns in certain groups will be more easily spotted.
• This Biobank is unique in its size, but there are others. Very many universities and hospitals round the world have data. Much published work is “ meta analysis “ of all other studies on a given illness.
• Anonymity is a double – edged sword. There’s no way of informing a participant if the data shows they’re at risk from a specific disease. Conversely, it should stop police or others trying to access information for solving crimes or in the interests of national security. Insurers would also like – but won’t get - information to know if their clients are at increased risk from illness.
• With such a massive project, quality control is not easy – reliability is vital for new drugs and health policies to be effective.
• This is a very expensive project. Information should be free for research workers, but drug companies and others who are looking for profit should have to pay.
• Ideally there will soon be obvious benefits, as more information becomes available about diseases and response to treatment. Some current treatments are crude – chemotherapy for cancer kills many normal cells, and major surgery has risks. The wish for the future is for “ personalised medicine “ with treatment tailored to individuals’ genetic blueprints - far safer and effective than at present. Let’s hope this Biobank is successful. Only time will tell – up to 30 years is planned – but it’s been greeted enthusiastically by the medical establishment.